Harmonized demographics data from the three National Drug Treatment Clinical Trials Network (CTN) opioid use disorder treatment trials (CTN-0027, CTN-0030, CTN-0051, , N= 2492)
| 27 (N=1269) |
30 (N=653) |
51 (N=570) |
Overall (N=2492) |
|
|---|---|---|---|---|
| Sex | ||||
| Hispanic | 206 (16.2%) | 31 (4.7%) | 99 (17.4%) | 336 (13.5%) |
| Not Hispanic | 1063 (83.8%) | 622 (95.3%) | 471 (82.6%) | 2156 (86.5%) |
| Age | ||||
| Mean (SD) | 36.9 (11.1) | 32.7 (10.2) | 33.9 (9.63) | 35.1 (10.7) |
| Median [Min, Max] | 35.0 [18.0, 67.0] | 30.0 [18.0, 77.0] | 31.0 [19.0, 67.0] | 33.0 [18.0, 77.0] |
| Ethnicity | ||||
| Hispanic | 206 (16.2%) | 31 (4.7%) | 99 (17.4%) | 336 (13.5%) |
| Not Hispanic | 1063 (83.8%) | 622 (95.3%) | 471 (82.6%) | 2156 (86.5%) |
| Refused/Missing | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Race | ||||
| Refused/Missing | 6 (0.5%) | 1 (0.2%) | 6 (1.1%) | 13 (0.5%) |
| Black | 128 (10.1%) | 21 (3.2%) | 73 (12.8%) | 222 (8.9%) |
| Other | 229 (18.0%) | 35 (5.4%) | 70 (12.3%) | 334 (13.4%) |
| White | 906 (71.4%) | 596 (91.3%) | 421 (73.9%) | 1923 (77.2%) |
| Education | ||||
| HS/GED | 59 (4.6%) | 253 (38.7%) | 228 (40.0%) | 540 (21.7%) |
| Less than HS | 45 (3.5%) | 102 (15.6%) | 123 (21.6%) | 270 (10.8%) |
| More than HS | 59 (4.6%) | 298 (45.6%) | 219 (38.4%) | 576 (23.1%) |
| Missing | 1106 (87.2%) | 0 (0%) | 0 (0%) | 1106 (44.4%) |
| Relationship Status | ||||
| Married or Partnered | 26 (2.0%) | 186 (28.5%) | 55 (9.6%) | 267 (10.7%) |
| Never married | 88 (6.9%) | 326 (49.9%) | 392 (68.8%) | 806 (32.3%) |
| Separated/Divorced/Widowed | 48 (3.8%) | 139 (21.3%) | 123 (21.6%) | 310 (12.4%) |
| Missing | 1107 (87.2%) | 2 (0.3%) | 0 (0%) | 1109 (44.5%) |
| Employment | ||||
| Full Time | 69 (5.4%) | 411 (62.9%) | 268 (47.0%) | 748 (30.0%) |
| Other | 7 (0.6%) | 16 (2.5%) | 24 (4.2%) | 47 (1.9%) |
| Part Time | 34 (2.7%) | 116 (17.8%) | 116 (20.4%) | 266 (10.7%) |
| Student | 1 (0.1%) | 28 (4.3%) | 10 (1.8%) | 39 (1.6%) |
| Unemployed | 52 (4.1%) | 82 (12.6%) | 151 (26.5%) | 285 (11.4%) |
| Missing | 1106 (87.2%) | 0 (0%) | 1 (0.2%) | 1107 (44.4%) |
| Usual Living Arragements | ||||
| Stable | 153 (12.1%) | 651 (99.7%) | 534 (93.7%) | 1338 (53.7%) |
| Not Stable | 9 (0.7%) | 2 (0.3%) | 36 (6.3%) | 47 (1.9%) |
| Refused/Missing | 1107 (87.2%) | 0 (0%) | 0 (0%) | 1107 (44.4%) |
Harmonized Urine Drug Screen (UDS) data from the three National Drug Treatment Clinical Trials Network (CTN) opioid use disorder treatment trials
| 27 (N=26721) |
30 (N=10364) |
51 (N=10258) |
Overall (N=47343) |
|
|---|---|---|---|---|
| Substance | ||||
| Amphetamine | 1150 (4.3%) | 254 (2.5%) | 310 (3.0%) | 1714 (3.6%) |
| Benzodiazepine | 3089 (11.6%) | 2049 (19.8%) | 1116 (10.9%) | 6254 (13.2%) |
| Cocaine | 6595 (24.7%) | 704 (6.8%) | 800 (7.8%) | 8099 (17.1%) |
| Methamphetamine | 1462 (5.5%) | 177 (1.7%) | 308 (3.0%) | 1947 (4.1%) |
| Opioid | 8317 (31.1%) | 1850 (17.9%) | 1111 (10.8%) | 11278 (23.8%) |
| Oxycodone | 947 (3.5%) | 2508 (24.2%) | 151 (1.5%) | 3606 (7.6%) |
| Propoxyphene | 173 (0.6%) | 164 (1.6%) | 0 (0%) | 337 (0.7%) |
| THC | 4988 (18.7%) | 2284 (22.0%) | 1795 (17.5%) | 9067 (19.2%) |
| Buprenorphine | 0 (0%) | 374 (3.6%) | 4420 (43.1%) | 4794 (10.1%) |
| Barbiturate | 0 (0%) | 0 (0%) | 227 (2.2%) | 227 (0.5%) |
| MDMA | 0 (0%) | 0 (0%) | 20 (0.2%) | 20 (0.0%) |
| 27 (N=20961) |
30 (N=6287) |
51 (N=8638) |
Overall (N=35886) |
|
|---|---|---|---|---|
| Temperature In Range | ||||
| No | 25 (0.1%) | 16 (0.3%) | 40 (0.5%) | 81 (0.2%) |
| Yes | 20732 (98.9%) | 6242 (99.3%) | 8598 (99.5%) | 35572 (99.1%) |
| Missing | 204 (1.0%) | 29 (0.5%) | 0 (0%) | 233 (0.6%) |
Medical and Psychiatric Co-Morbidities in the three National Drug Treatment Clinical Trials Network (CTN) opioid use disorder treatment trials
| 27 (N=1269) |
30 (N=653) |
51 (N=570) |
Overall (N=2492) |
|
|---|---|---|---|---|
| History of Schiziphrenia | ||||
| Yes | 32 (2.5%) | 8 (1.2%) | 7 (1.2%) | 47 (1.9%) |
| No | 1235 (97.3%) | 645 (98.8%) | 563 (98.8%) | 2443 (98.0%) |
| Missing/Not Answered | 2 (0.2%) | 0 (0%) | 0 (0%) | 2 (0.1%) |
| History of Major Depression | ||||
| Yes | 352 (27.7%) | 215 (32.9%) | 179 (31.4%) | 746 (29.9%) |
| No | 917 (72.3%) | 438 (67.1%) | 391 (68.6%) | 1746 (70.1%) |
| Missing/Not Answered | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| History of Bipolar Disorder | ||||
| Yes | 147 (11.6%) | 37 (5.7%) | 79 (13.9%) | 263 (10.6%) |
| No | 1121 (88.3%) | 615 (94.2%) | 491 (86.1%) | 2227 (89.4%) |
| Missing/Not Answered | 1 (0.1%) | 1 (0.2%) | 0 (0%) | 2 (0.1%) |
| History of Anxiety/Panic Disorder | ||||
| Yes | 382 (30.1%) | 204 (31.2%) | 257 (45.1%) | 843 (33.8%) |
| No | 886 (69.8%) | 448 (68.6%) | 313 (54.9%) | 1647 (66.1%) |
| Missing/Not Answered | 1 (0.1%) | 1 (0.2%) | 0 (0%) | 2 (0.1%) |
| History of Brain Damage | ||||
| Yes | 115 (9.1%) | 119 (18.2%) | 69 (12.1%) | 303 (12.2%) |
| No | 1151 (90.7%) | 534 (81.8%) | 501 (87.9%) | 2186 (87.7%) |
| Missing/Not Answered | 3 (0.2%) | 0 (0%) | 0 (0%) | 3 (0.1%) |
| History of Epilepsy | ||||
| Yes | 40 (3.2%) | 22 (3.4%) | 49 (8.6%) | 111 (4.5%) |
| No | 1229 (96.8%) | 631 (96.6%) | 521 (91.4%) | 2381 (95.5%) |
| Missing/Not Answered | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| DSM Opiate Diagnosis | ||||
| Yes | 1268 (99.9%) | 653 (100%) | 570 (100%) | 2491 (100.0%) |
| No | 1 (0.1%) | 0 (0%) | 0 (0%) | 1 (0.0%) |
| Missing/Not Answered | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| DSM Alcohol Diagnosis | ||||
| Yes | 251 (19.8%) | 0 (0%) | 159 (27.9%) | 410 (16.5%) |
| No | 843 (66.4%) | 0 (0%) | 411 (72.1%) | 1254 (50.3%) |
| Missing/Not Answered | 175 (13.8%) | 653 (100%) | 0 (0%) | 828 (33.2%) |
| DSM Amphetamine Diagnosis | ||||
| Yes | 120 (9.5%) | 0 (0%) | 106 (18.6%) | 226 (9.1%) |
| No | 974 (76.8%) | 0 (0%) | 464 (81.4%) | 1438 (57.7%) |
| Missing/Not Answered | 175 (13.8%) | 653 (100%) | 0 (0%) | 828 (33.2%) |
| DSM Cannabis Diagnosis | ||||
| Yes | 223 (17.6%) | 0 (0%) | 163 (28.6%) | 386 (15.5%) |
| No | 871 (68.6%) | 0 (0%) | 407 (71.4%) | 1278 (51.3%) |
| Missing/Not Answered | 175 (13.8%) | 653 (100%) | 0 (0%) | 828 (33.2%) |
| DSM Cocaine Diagnosis | ||||
| Yes | 357 (28.1%) | 0 (0%) | 175 (30.7%) | 532 (21.3%) |
| No | 737 (58.1%) | 0 (0%) | 394 (69.1%) | 1131 (45.4%) |
| Missing/Not Answered | 175 (13.8%) | 653 (100%) | 1 (0.2%) | 829 (33.3%) |
| DSM Sedatives Diagnosis | ||||
| Yes | 153 (12.1%) | 0 (0%) | 153 (26.8%) | 306 (12.3%) |
| No | 941 (74.2%) | 0 (0%) | 417 (73.2%) | 1358 (54.5%) |
| Missing/Not Answered | 175 (13.8%) | 653 (100%) | 0 (0%) | 828 (33.2%) |
#> R version 4.4.1 (2024-06-14)
#> Platform: x86_64-pc-linux-gnu
#> Running under: Ubuntu 24.04.1 LTS
#>
#> Matrix products: default
#> BLAS: /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
#> LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.26.so; LAPACK version 3.12.0
#>
#> locale:
#> [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
#> [3] LC_TIME=en_US.UTF-8 LC_COLLATE=C
#> [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
#> [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
#> [9] LC_ADDRESS=C LC_TELEPHONE=C
#> [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
#>
#> time zone: Etc/UTC
#> tzcode source: system (glibc)
#>
#> attached base packages:
#> [1] stats graphics grDevices utils datasets methods base
#>
#> other attached packages:
#> [1] public.ctn0094data_1.0.6 psych_2.4.6.26 infer_1.0.7
#> [4] janitor_2.2.0 kableExtra_1.4.0 broom_1.0.7
#> [7] DiagrammeR_1.0.11 table1_1.4.3 ggthemes_5.1.0
#> [10] forcats_1.0.0 tibble_3.2.1 ggplot2_3.5.1
#> [13] dplyr_1.1.4 conflicted_1.2.0 rmarkdown_2.28
#>
#> loaded via a namespace (and not attached):
#> [1] gtable_0.3.6 xfun_0.49 bslib_0.8.0 htmlwidgets_1.6.4
#> [5] visNetwork_2.1.2 lattice_0.22-6 vctrs_0.6.5 tools_4.4.1
#> [9] generics_0.1.3 parallel_4.4.1 fansi_1.0.6 pkgconfig_2.0.3
#> [13] RColorBrewer_1.1-3 lifecycle_1.0.4 compiler_4.4.1 stringr_1.5.1
#> [17] munsell_0.5.1 mnormt_2.1.1 snakecase_0.11.1 htmltools_0.5.8.1
#> [21] sys_3.4.3 buildtools_1.0.0 sass_0.4.9 yaml_2.3.10
#> [25] Formula_1.2-5 pillar_1.9.0 jquerylib_0.1.4 tidyr_1.3.1
#> [29] cachem_1.1.0 nlme_3.1-166 tidyselect_1.2.1 digest_0.6.37
#> [33] stringi_1.8.4 purrr_1.0.2 maketools_1.3.1 fastmap_1.2.0
#> [37] grid_4.4.1 colorspace_2.1-1 cli_3.6.3 magrittr_2.0.3
#> [41] utf8_1.2.4 withr_3.0.2 scales_1.3.0 backports_1.5.0
#> [45] lubridate_1.9.3 timechange_0.3.0 memoise_2.0.1 evaluate_1.0.1
#> [49] knitr_1.48 viridisLite_0.4.2 rlang_1.1.4 glue_1.8.0
#> [53] xml2_1.3.6 svglite_2.1.3 rstudioapi_0.17.1 jsonlite_1.8.9
#> [57] R6_2.5.1 systemfonts_1.1.0